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. 2021 May 24;12(6):532. doi: 10.1038/s41419-021-03814-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A PEPT1 expression data were provided by TCGA in GEPIA. Box plots showed PEPT1 mRNA expression in CRC tumor tissues (T) and normal tissues (N). *P < 0.05, one-tailed unpaired t-test. B The mRNA expression of PEPT1 was detected in 58 pairs of CRC and corresponding adjacent non-tumorous tissues by RT-qPCR. Data are shown as means ± SD, n = 58. C The fold change log2(T/N) of PEPT1 expression between 58 pairs of CRC and adjacent normal tissues were summarized. <−1 is downregulation, −1 to 1 is unchanged and >1 is upregulation. D Representative images of western blotting analysis for the expression of PEPT1 in 14 paired samples of CRC. GAPDH was used as a loading control.