TABLE 3.

Spearman’s rank correlation between ePR-EDSS — NS-EDSS functional system scores in Cohorts 1 and 2 (n = 50 and n = 86, respectively)

Spearman’s rank correlation rho (p)	Cohort 1					Cohort 2
Functional System	All (n=50)	EDSS 0 – 1.5 (n=15)	EDSS 2 – 3.5 (n=24)	EDSS 4 – 5.5 (n=7)	EDSS 6.0 + (n=4)	All (n=86)	EDSS 0 – 1.5 (n=23)	EDSS 2 – 3.5 (n=22)	EDSS 4 – 5.5 (n=21)	EDSS 6.0 + (n=20)
Visual	0.17 (0.23)	0.38 (0.16)	0.10 (0.63)	0.11 (0.82)	NA	0.38 (<0.001)	−0.25 (0.24)	0.33 (0.15)	0.35 (0.12)	0.58 (0.0079)
Brainstem	0.46 (<0.001)	0.42 (0.12)	0.40 (0.050)	−0.35 (0.44)	1 (<0.001)	0.37 (<0.001)	0.40 (0.056)	0.14 (0.53)	0.31 (0.17)	0.52 (0.018)
Pyramidal	0.36(0.0093)	−0.47 (0.079)	0.26 (0.22)	0.23 (0.61)	0.82 (0.18)	0.67 (<0.001)	0.066 (0.77)	0.36 (0.099)	0.65 (0.0015)	0.21 (0.39)
Cerebellar	0.54 (<0.001)	−0.13 (0.63)	0.34 (0.10)	0.083 (0.86)	−0.27 (0.73)	0.53 (<0.001)	−0.083 (0.71)	−0.13 (0.55)	0.27 (0.24)	0.069 (0.79)
Sensory	0.28 (0.049)	−0.20 (0.47)	0.16 (0.45)	0.0095 (0.98)	NA	0.45 (<0.001)	−0.17 (0.44)	0.59 (0.0042)	0.011 (0.96)	0.29 (0.21)
Bowel & Bladder	0.79 (<0.001)	0.33 (0.24)	0.75 (<0.001)	0.81 (0.026)	1 (<0.001)	0.71 (<0.001)	0.39 (0.066)	0.78 (<0.001)	0.24 (0.29)	0.44 (0.052)
Cerebral	0.37 (0.0079)	−0.35 (0.21)	0.52 (0.0088)	0.16 (0.74)	0.27 (0.73)	0.55 (<0.001)	0.11 (0.60)	0.39 (0.069)	0.54 (0.012)	0.63 (0.0030)

^*In the Table EDSS refers to the NS-EDSS