Table 1.
Baseline characteristics of the two patient cohorts
| SCD Patients N = 39 | Healthcare professionals N = 121 | P-value | |
|---|---|---|---|
| Age, y, mean (range) | 35 (18–64) | 35 (21–53) | 0.468 |
| Sex, n (%) | |||
| Male | 17(43) | 50 (42) | 0.802 |
| Female | 22 (56) | 71 (59) | |
| Smoking > 5 p/year, n (%) | 3 (8) | 19 (16) | 0.175 |
| Diabetes, n (%) | 0 | 3 (2) | N/A |
| Hypertension, n (%) | 0 | 3 (2) | N/A |
| COPD, n (%) | 2 (2) | 5 (4) | 0.653 |
| Sickle cell related, n (%) | |||
| Hemoglobin genotype | |||
| SS/Sβ6 | 23 (59) | N/A | |
| Sβ+ | 15 (39) | N/A | |
| SE | 1 (2) | N/A | |
| Hydroxyurea treatment | 25 (64) | N/A | |
| ACE treatment at admission | 13 (33) | N/A | |
| ASA treatment at admission | 18 (46) | N/A | |
| Transfusion in last 3 months | 8 (20) | N/A | |
| Pulmonary hypertension | 4 (10) | N/A | |
| Neurological attack | 15 (38) | N/A | |
| Acute chest syndrome history | 5 (13) | N/A | |
SCD, sickle cell disease; COPD, chronic obstructive pulmonary disease; ACE, angiotensin converting enzyme; ASA, acetyl salicytic acid