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. 2021 May 11;8:627741. doi: 10.3389/fcvm.2021.627741

Table 6.

Multivariable odds ratios of demographic, geographic, and anthropometric factors and obesity for childhood hypertension and phenotypes.

Characteristic Prehypertension Hypertension Stage 1 hypertension Stage 2 hypertension ISH IDH SDH
OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P
SURVEY YEAR
1993 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
1997 1.17 (0.91–1.52) 0.226 1.09 (0.86–1.37) 0.484 1.11 (0.88–1.41) 0.380 0.74 (0.30–1.83) 0.517 1.93 (0.94–3.96) 0.073 0.97 (0.74–1.26) 0.800 1.25 (0.72–2.17) 0.428
2000 1.23 (0.96–1.59) 0.106 1.17 (0.93–1.46) 0.188 1.20 (0.95–1.51) 0.133 0.75 (0.31–1.82) 0.530 1.78 (0.86–3.68) 0.118 1.08 (0.83–1.40) 0.556 1.30 (0.75–2.27) 0.348
2004 1.33 (1.01–1.75) 0.043 1.61 (1.27–2.04) <0.001 1.65 (1.30–2.10) <0.001 1.00 (0.39–2.54) 1.000 2.73 (1.30–5.71) 0.008 1.58 (1.22–2.06) 0.001 1.13 (0.61–2.12) 0.695
2006 1.18 (0.88–1.58) 0.276 0.89 (0.68–1.17) 0.413 0.95 (0.72–1.26) 0.708 0.21 (0.05–0.97) 0.045 1.35 (0.58–3.14) 0.489 0.85 (0.62–1.16) 0.311 0.79 (0.40–1.57) 0.499
2009 1.61 (1.21–2.16) 0.001 1.60 (1.24–2.07) <0.001 1.60 (1.23–2.08) 0.001 1.57 (0.67–3.68) 0.296 2.03 (0.93–4.45) 0.076 1.60 (1.20–2.13) 0.001 1.31 (0.69–2.49) 0.410
2011 1.35 (1.02–1.78) 0.035 1.12 (0.87–1.44) 0.377 1.18 (0.92–1.53) 0.192 0.33 (0.11–1.05) 0.060 1.19 (0.54–2.62) 0.666 1.11 (0.84–1.47) 0.475 1.10 (0.60–2.00) 0.754
2015 2.14 (1.62–2.85) <0.001 2.08 (1.61–2.67) <0.001 2.09 (1.61–2.71) <0.001 1.53 (0.65–3.59) 0.327 2.48 (1.17–5.25) 0.018 2.16 (1.63–2.86) <0.001 1.37 (0.73–2.55) 0.324
AGE GROUP
7–12 years 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
13–17 years 2.08 (1.82–2.37) <0.001 1.76 (1.56–1.97) <0.001 1.81 (1.61–2.03) <0.001 1.02 (0.63–1.63) 0.939 1.57 (1.15–2.14) 0.004 2.02 (1.77–2.31) <0.001 0.92 (0.69–1.22) 0.553
SEX
Male 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
Female 0.83 (0.73–0.95) 0.005 0.92 (0.82–1.03) 0.160 0.91 (0.81–1.03) 0.126 1.08 (0.69–1.70) 0.743 1.19 (0.87–1.63) 0.279 0.86 (0.75–0.98) 0.025 1.01 (0.77–1.33) 0.927
LOCATION
Urban 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
Rural 1.08 (0.94–1.25) 0.283 0.94 (0.83–1.07) 0.358 0.94 (0.83–1.07) 0.346 1.03 (0.63–1.67) 0.918 1.42 (0.99–2.04) 0.055 0.86 (0.75–0.99) 0.042 1.16 (0.86–1.58) 0.328
REGION
North 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
South 0.94 (0.82–1.08) 0.401 0.65 (0.58–0.73) <0.001 0.65 (0.57–0.73) <0.001 0.70 (0.44–1.12) 0.134 1.10 (0.78–1.55) 0.576 0.59 (0.52–0.68) <0.001 0.76 (0.58–1.02) 0.063
BMI (kg/m2) 1.06 (1.02–1.10) 0.003 1.10 (1.07–1.14) <0.001 1.10 (1.07–1.14) <0.001 1.04 (1.01–1.08) 0.014 1.05 (1.00–1.10) 0.044 1.08 (1.04–1.12) <0.001 1.12 (1.01–1.24) 0.030
WC (cm) 1.02 (1.01–1.03) <0.001 1.02 (1.01–1.03) <0.001 1.02 (1.01–1.03) <0.001 1.03 (1.01–1.06) 0.012 1.04 (1.02–1.06) <0.001 1.02 (1.01–1.03) <0.001 1.00 (0.98–1.02) 0.804
GENERAL OBESITY
Normal 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
Overweight 1.26 (1.00–1.59) 0.051 1.66 (1.38–2.01) <0.001 1.68 (1.39–2.04) <0.001 1.25 (0.56–2.76) 0.584 1.48 (0.84–2.59) 0.172 1.54 (1.24–1.91) <0.001 2.47 (1.62–3.77) <0.001
Obesity 2.00 (1.47–2.73) <0.001 2.69 (2.10–3.44) <0.001 2.62 (2.03–3.38) <0.001 3.68 (1.82–7.44) <0.001 3.56 (2.03–6.22) <0.001 1.83 (1.36–2.47) <0.001 7.27 (4.57–11.59) <0.001
CENTRAL OBESITY
Normal 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref 1 Ref
Central Obesity 1.18 (0.91–1.53) 0.203 1.49 (1.21–1.83) <0.001 1.43 (1.16–1.78) 0.001 2.76 (1.48–5.14) 0.001 2.43 (1.48–3.99) <0.001 1.50 (1.19–1.90) 0.001 1.08 (0.69–1.72) 0.728

*Values were odds ratio (95% confidence interval); Odds ratio for each variable was adjusted for all other variables in the table; Ref, reference; BMI, Body Mass Index; WC, Waist Circumference;The comparisons were between hypertension groups and normotensives; The multivariable generalized estimating equations (GEE) logistic regression adjusted all variables listed.