Skip to main content
. 2021 May 24;11:10802. doi: 10.1038/s41598-021-90198-3

Table 2.

Presence of S. mutans, its molecular characterization, and presence of Candida spp.

Variable Groups All subjects
(n = 143)
CF (n = 73)
n (%)
CE-NR (n = 45)
n (%)
CR (n = 25)
n (%)
P value*
S. mutans presence 11 (15.1) 14 (31.1) 20 (80.0)  < .0001 45 (31.5)
Serotype distribution
Ser c only 6 (8.2) 8 (17.8) 15 (60.0)  < .0001 29 (20.3)
Ser e only 1 (1.4) 2 (4.4) 1 (4.0) .56 4 (2.8)
Ser f only 0 (0.0) 1 (2.2) 0 (0.0) .33 1 (0.7)
Ser k only 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Ser c + e 1 (1.4) 3 (6.7) 0 (0.0) .15 4 (2.8)
Ser e + k 3 (4.1) 0 (0.0) 4 (16.0) .01 7 (4.9)
Genes coding for Collagen Binding Proteins
Cbp (cnm + cbm) 0 (0.0) 0 (0.0) 7 (28.0)  < .0001 7 (4.9)
cnm 0 (0.0) 0 (0.0) 5 (20.0) .0002 6 (4.2)
cbm 0 (0.0) 0 (0.0) 2 (8.0) .03 2 (1.4)
Candida spp. presence 29 (39.7) 16 (35.6) 20 (80.0) .0007 65 (45.5)
Candida albicans presence 15 (20.6) 9 (20.0) 17 (68.0)  < .0001 41 (28.7)
Presence of more than one species of Candida 9 (12.3) 2 (4.4) 5 (20.0) .30 16 (11.2)
Co-infection with S. mutans and C. albicans 7 (9.6) 7 (15.6) 17 (68.0)  < .0001 31 (21.7)

CF caries free, CE-NR caries experienced—no recurrence, CR active caries—recurrence.

*P-values based on Cochran-Mantel–Haenszel test of general association, controlling for age by stratification.