Skip to main content
. 2021 May 24;11:10825. doi: 10.1038/s41598-021-90402-4

Table 1.

Information and references for the antigens used in the study and the technology involved in their analysis.

Antigens/Epitopes References Main characteristics Analytical methods
Synthetic Multianalysis profiling Surface plasmon resonance Western Blotting/ELISA***
Biotin Sulfone Tagged Oligomannosides (BSTOs), schematic representation of the epitope
Manα-1,2Man X X X
Manα-1,2Manα-1,2Manα-1,2Man X
Manβ-1,2Man X
Manβ-1,2Manβ-1,2Man Mat & Meths Synthesized for the present study X
Manβ-1,2Manβ-1,2Manβ-1,2Man X X X
Native

Phosphopeptidomannan (mannan)

From C. albicans VW32 (Serotype A)

27, 3133, 55 Complex cell wall surface polymer. Structure determined by NMR and sequential depolymerization of constitutive oligomannosides used for diagnostic purposes ***
Phospholipomannan 18, 56, 57

Glycoplipid of the mannoinositolphospho ceramide family

Present at cell wall surface

Shed in contact with host cells and has immunomodulatory properties

X
From C. albicans VW 32 (serotype A) 19 Polysaccharide moiety consisting of β-mannosides up to 14 residues X
From C. albicans NIH-B (serotype B) 20 Polysaccharide moiety consisting of β-1,2 mannotriose X
From C. albicans BPW17 (serotype A) 58 PLM identical to that of VW32. Used for genetic manipulations X
From C. albicans BPW17 depleted in bmt6 21 Polysaccharide moiety truncated with a β-mannotriose X