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. 2021 May 24;12:3039. doi: 10.1038/s41467-021-23171-3

Fig. 5. Overview of somatic WGS variants in the longitudinal cohort.

Fig. 5

a Tumor mutation burden (non-synonymous SNVs and small indels/MB) in the longitudinal cohort samples. b Stacked bar plots showing the frequency of SVs, including indels (>25 bp) and breakpoints in each sample. c The number of genes with copy number alterations in each sample. The plot displays the number of genes that show a z-transformed copy number ≥2 (gain) or ≤−2 (loss). d Oncoprint displaying somatic variants affecting COSMIC cancer census genes. The plot displays SNVs and small indels with VAF > 0.05, large indels and breakpoints affecting exons, and CNVs with z-transformed copy number ≥2 (gain) or ≤−2 (loss).