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. 2021 Mar 30;124(11):1843–1853. doi: 10.1038/s41416-021-01362-5

Fig. 6. ITGA6-AS1 reduced invasion by regulating ITGA6 expression in MM cells.

Fig. 6

a The invasion of cells in transiently transfected with vector control or overexpression of ITGA6-AS1 was detected by transwell invasion assays. Representative images are shown, and invasive cells were counted. Scale bar, 100 μm. The results are presented as the mean ± SD from three independent experiments (n = 3). b The expression of ITGA6 was detected in each treatment group by qPCR and western blot. The results are presented as the mean ± SD from three independent experiments (n = 3). c The changes in invasion following transfection with ITGA6-AS1 overexpression vector alone or in combination with ITGA6 siRNA were investigated through transwell assays. Cells were counted, and representative images was shown (n = 3). Scale bar, 100 μm. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns not significant versus control cells.