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. 2021 May 11;12:661304. doi: 10.3389/fphar.2021.661304

TABLE 3.

Physiological development index in each different group.

Observation Vehicle (n = 14) Nicotine (n = 8–17) Effect
Smell pups (%)
 PND11 85% 18%
 PND12 100% 76% P < 0.001****
 PND13 100% 100%
Hearing pups (%)
 PND11 64% 0.0
 PND12 86% 50% p = 0.002**
 PND13 100% 75%
 PND14 100% 100%
Eye opening pups (%)
 PND11 0.0 0.0
 PND12 21% 0.0
 PND13 100% 0.0 P < 0.0001****
 PND14 100% 5%
 PND15 100% 82%
 PND16 100% 100%