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. 2021 May 11;12:670992. doi: 10.3389/fimmu.2021.670992

Figure 9.

Figure 9

Cytokine profiles in the supernatant of co-culture lymphoproliferation (IFN-γ and IL-2 cytokines represented in A, B respectively). The supernatants come from the co-cultures of lymphocytes from infected mice and BMDCs pulsed with peptides and cytokine levels were analyzed by ELISE. Lymphocytes cultivated in the absence of stimulus (Lympho) were used as negative control, lymphocytes cultivated with Concanavalin A were used as positive control (ConA), and co-culture with BMDCs without be pulsed with peptide and lymphocytes without ConA (Limpho+DC) were the control groups. The data shown are from two independent experiments. Data were analyzed by one-way ANOVA followed by Tukey’s post-test and confirmed by “t” test, ****p < 0.0001 in comparison to co-culture of BMDCs and lymphocytes without stimulus (Lympho+DC).