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In vitro cytotoxicity of indole derivatives (1a–1j) on normal cellsa.
| Compounds | MRC5 | HEK-293 | LO2 |
| IC50 (μm) | IC50 (μm) | IC50 (μm) | |
| 1a | 76.36 | 70.06 | 67.48 |
| 1b | 67.21 | 62.12 | 72.17 |
| 1c | 86.66 | 81.14 | 87.10 |
| 1d | 56.25 | 79.14 | 66.24 |
| 1e | 72.76 | 57.09 | 56.01 |
| 1f | 51.24 | 66.17 | 68.24 |
| 1g | 62.61 | 58.24 | 70.54 |
| 1h | 66.32 | 67.01 | 58.22 |
| 1i | 79.41 | 77.44 | 66.70 |
| 1j | 75.14 | 52.71 | 70.12 |
aEach compound was tested in triplicate. All error bars represent mean ± SD from three independent experiments.
