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. 2021 May 11;12:680636. doi: 10.3389/fphar.2021.680636

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Copyright © 2021 Chen, Li, Fan, Geng, Zhao, Wang, Zhang, Tang, Wang and Meng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of DXK on the protein levels of Mapk10, RASGRF1, RASA3, Ras, and IGF-IR in the hippocampus of rats with brain injury induced by CHH. Representative microphotographs of immunofluorescence staining (400×) for identification of Mapk10 (A), RASGRF1 (B), RASA3 (C), Ras (D), and IGF-IR (E) (red color); average optical of Mapk10 (F), RASGRF1 (G), RASA3 (H), Ras (I), and IGF-IR (J). Data were expressed as the mean ± SD (n = 6). **p < 0.01 vs. the control group; ^# p < 0.05, ^## p < 0.01 vs. the model group. DXK, Duoxuekang; NDK, Nuodikang capsule.