Table 2.
The correlation between ABI1-TSV-11 expression and clinicopathological characteristics of CRC, LsCC and RsCC patients from TCGA.
| Characteristics | CRC | LsCC | RsCC | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Low/high | χ2 | P | n | Low/high | χ2 | P | n | Low/high | χ2 | P | |
| Sex | 339 | 3.027 | 0.082 | 168 | 2.914 | 0.088 | 154 | 1.765 | 0.184 | |||
| Male | 98/88 | 41/43 | 48/42 | |||||||||
| Female | 95/58 | 52/32 | 41/23 | |||||||||
| Age | 339 | 1.039 | 0.308 | 168 | 5.154 | 0.023 | 154 | 0.499 | 0.480 | |||
| < 65 | 102/69 | 62/37 | 36/30 | |||||||||
| ≥ 65 | 91/77 | 31/38 | 53/35 | |||||||||
| Race | 309 | 0.328 | 0.849 | 149 | 2.741 | 0.254 | 143 | 2.673 | 0.263 | |||
| Asian | 5/5 | 3/0 | 2/5 | |||||||||
| Black | 34/23 | 12/7 | 22/14 | |||||||||
| White | 140/102 | 70/57 | 59/41 | |||||||||
| Clinical stage | 323 | 0.207 | 0.649 | 160 | 0.243 | 0.622 | 146 | 0.027 | 0.869 | |||
| I + II | 100/72 | 45/34 | 49/36 | |||||||||
| III + IV | 84/67 | 43/38 | 36/25 | |||||||||
| Infiltration depth | 337 | 0.985 | 0.321 | 167 | 1.374 | 0.241 | 154 | 0.001 | 0.977 | |||
| T1 + T2 | 39/23 | 19/10 | 19/14 | |||||||||
| T3 + T4 | 154/12 | 74/64 | 70/51 | |||||||||
| Lymph-node metastasis | 337 | 2.550 | 0.279 | 166 | 5.985 | 0.050 | 154 | 0.073 | 0.964 | |||
| N0 | 107/78 | 47/36 | 54/39 | |||||||||
| N1 | 55/35 | 36/21 | 15/12 | |||||||||
| N2 | 30/32 | 9/17 | 20/14 | |||||||||
| Distant metastasis | 275 | 0.025 | 0.874 | 141 | 0.132 | 0.717 | 121 | 0.330 | 0.566 | |||
| M0 | 129/99 | 65/51 | 59/44 | |||||||||
| M1 | 26/21 | 15/10 | 9/9 | |||||||||
| KRAS mutation | 55 | 0.009 | 0.925 | 28 | 0.084a | 21 | 0.080b | |||||
| No | 18/9 | 9/6 | 8/2 | |||||||||
| Yes | 19/9 | 12/1 | 4/7 | |||||||||
a–b fisher exact test.All others are Chi-square tests.
CRC colorectal cancer, DFS disease-free survival, LsCC left-sided colorectal cancer, OS over-all survival, RsCC right-sided colorectal cancer.