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. 2021 May 24;11:10782. doi: 10.1038/s41598-021-90324-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Overexpression of Wnt7b rescues diminished bone size in Bmpr1a-deficient mice. (A) Representative 3D reconstruction of cross-sectional μCT images at the proximal femur in littermate mice at P33. (B–D) μCT quantification of cortical bone parameters in the proximal femur. *: P < 0.05, two-way ANOVA, n = 5 (4 females, 1 male). (E) Representative 3D reconstruction of cross-sectional μCT images of the tibia immediately above the tibiofibular junction. (F–H) μCT quantification of cortical bone parameters of the tibia immediately above tibiofibular junction. *: P < 0.05, two-way ANOVA, n = 6 (4 females, 2 males).