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. 2021 May 11;12:667024. doi: 10.3389/fphys.2021.667024

TABLE 8.

Indirect desaturation indexes of the desaturases in the fatty acids of the phospholipids from healthy subjects and COVID-19 patients.

Desaturation index Healthy subjects COVID-19 patients p
C16:1n-7/C16:0 (Δ9) 0.11 ± 0.01 0.08 ± 0.007 0.006
C18:1n-9/C18:0 (Δ9) 4.91 ± 0.27 2.61 ± 0.11 0.001
γ-C18:3n-6/C18:2n-6 (Δ6) 0.009 ± 0.001 0.01 ± 0.002 NS
C20:4n-6/C20:3n-6 (Δ5) 2.69 ± 0.61 1.20 ± 0.13 0.001
C22:6n-3/C20:5n-3 (Δ5) 0.19 ± 0.19 0.39 ± 0.13 NS

Fatty acid nomenclature: C16:0, palmitic acid; C16:1n-7, palmitoleic acid; C18:0, stearic acid; C18:1n-9, oleic acid; C18:2n-6, linoleic acid; γ-C18:3n-6, γ-linolenic acid; α-C18:3n-3, α-linolenic acid; C20:3n-6, dihomo-γ-linolenic acid; C20:4n-6, arachidonic acid; C20:5n-3 eicosapentaenoic acid; C22:6n-3, docosahexaenoic acid. Data are mean ± SE (healthy subjects n = 22) (COVID-19 patients n = 42). The bold values indicate significant changes.