Table 3.
Uni- and multi-variate analysis of the number of cycles and other baseline variables as potential predictors of complete response.
Variable | Complete pathologic response | |||||
---|---|---|---|---|---|---|
Univariate | Multivariate | |||||
OR | 95% CI | p-value | aOR | 95% CI | p-value | |
Number of cycles | 0.97 | 0.46, 1.96 | 0.941 | – | – | – |
Clinical T stage | ||||||
<=2 | Reference | – | Reference | |||
>=3 | 1.47 | 0.77, 2.78 | 0.243 | – | – | – |
Sex | ||||||
Male | Reference | – | Reference | |||
Female | 0.75 | 0.29, 1.73 | 0.512 | – | – | – |
Age | 0.98 | 0.95, 1.01 | 0.158 | – | – | – |
Ecog | 0.81 | 0.53, 1.16 | 0.254 | – | – | – |
Charlson index | 0.96 | 0.81, 1.13 | 0.648 | – | – | – |
HB (g/dl) | 1.00 | 0.98, 1.02 | 0.647 | – | – | – |
Creatinine (mg/dl) | 0.80 | 0.39, 1.36 | 0.460 | – | – | – |
PCR (mg/L) | 1.00 | 0.96, 1.03 | 0.931 | – | – | – |
VES (mm/h) | 0.98 | 0.95, 1.00 | 0.043 | 0.98 | 0.95, 1.00 | 0.084 |
NLR | 0.93 | 0.75, 1.12 | 0.450 | – | – | – |
Neutrophils x10^3/µL | 1.01 | 0.97, 1.04 | 0.519 | – | – | – |
Lymphocytes x10^3/µL | 1.05 | 0.94, 1.17 | 0.364 | – | – | – |
Monocytes x10^3/µL | 1.30 | 1.06, 1.62 | 0.012 | 1.28 | 1.04, 1.58 | 0.019 |
Eosinophils x10^3/µL | 1.03 | 0.42, 1.87 | 0.932 | – | – | – |
Basophils x10^3/µL | 0.19 | 0.00, 64.7 | 0.599 | – | – | – |
Platelets x10^3/µL | 1.00 | 1.00, 1.00 | 0.499 | – | – | – |
Albumin (g/dl) | 1.13 | 0.61, 2.10 | 0.703 | – | – | – |
BMI | 1.05 | 0.96, 1.15 | 0.269 | – | – | – |
Total cholesterol level (mg/dl) | 1.00 | 1.00, 1.01 | 0.281 | – | – | – |
HDL (mg/dl) | 1.00 | 0.97, 1.02 | 0.709 | – | – | – |
Fibrinogen level (mg/dl) | 0.91 | 0.69, 1.18 | 0.491 | – | – | – |
Preoperative PCR (mg/L) | 0.99 | 0.94, 1.04 | 0.719 | – | – | – |
P-values and OR are computed with single and multiple logistic regression. Significant values are highlighted in bold.