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. 2021 May 11;11:651745. doi: 10.3389/fonc.2021.651745

Table 3.

Uni- and multi-variate analysis of the number of cycles and other baseline variables as potential predictors of complete response.

Variable Complete pathologic response
Univariate Multivariate
OR 95% CI p-value aOR 95% CI p-value
Number of cycles 0.97 0.46, 1.96 0.941
Clinical T stage
 <=2 Reference Reference
 >=3 1.47 0.77, 2.78 0.243
Sex
 Male Reference Reference
 Female 0.75 0.29, 1.73 0.512
Age 0.98 0.95, 1.01 0.158
Ecog 0.81 0.53, 1.16 0.254
Charlson index 0.96 0.81, 1.13 0.648
HB (g/dl) 1.00 0.98, 1.02 0.647
Creatinine (mg/dl) 0.80 0.39, 1.36 0.460
PCR (mg/L) 1.00 0.96, 1.03 0.931
VES (mm/h) 0.98 0.95, 1.00 0.043 0.98 0.95, 1.00 0.084
NLR 0.93 0.75, 1.12 0.450
Neutrophils x10^3/µL 1.01 0.97, 1.04 0.519
Lymphocytes x10^3/µL 1.05 0.94, 1.17 0.364
Monocytes x10^3/µL 1.30 1.06, 1.62 0.012 1.28 1.04, 1.58 0.019
Eosinophils x10^3/µL 1.03 0.42, 1.87 0.932
Basophils x10^3/µL 0.19 0.00, 64.7 0.599
Platelets x10^3/µL 1.00 1.00, 1.00 0.499
Albumin (g/dl) 1.13 0.61, 2.10 0.703
BMI 1.05 0.96, 1.15 0.269
Total cholesterol level (mg/dl) 1.00 1.00, 1.01 0.281
HDL (mg/dl) 1.00 0.97, 1.02 0.709
Fibrinogen level (mg/dl) 0.91 0.69, 1.18 0.491
Preoperative PCR (mg/L) 0.99 0.94, 1.04 0.719

P-values and OR are computed with single and multiple logistic regression. Significant values are highlighted in bold.