Table 2.

Peak areas of differential metabolites after the total area normalization.

Metabolites	ASD group		Control group		P-value*	FDR P-value*	Fold change
	Mean	SD	Mean	SD
3-Aminoisobutanoic acid	0.77	0.61	0.94	0.68	0.0425	0.0921	0.82
Alanine	0.52	0.16	0.51	0.17	0.8440	0.9975	1.01
Taurine	0.63	0.21	0.62	0.17	0.9162	0.9162	1.00
Glycine	1.24	0.39	1.19	0.44	0.3430	0.4459	1.04
Guanidinoacetic acid	1.42	0.32	1.36	0.36	0.1446	0.2350	1.05
Creatine	1.78	0.86	1.43	0.72	0.0009	0.0039	1.24
Creatinine	4.68	0.90	5.26	1.21	<0.0001	0.0012	0.89
Hydroxyphenylacetylglycine	0.15	0.06	0.15	0.06	0.8860	0.9598	1.01
Phenylacetylglycine	0.48	0.20	0.44	0.21	0.1097	0.2037	1.10
Hypoxanthine	0.02	0.01	0.04	0.03	<0.0001	0.0007	0.62
Formate	0.06	0.04	0.05	0.02	0.0267	0.0694	1.17
N-methylnicotinamide	0.01	0.01	0.01	0.01	0.0149	0.0484	0.79
Unknown	0.26	0.34	0.22	0.18	0.3109	0.4491	1.16

^*Bold value indicate that the difference was considered statistically significant (P < 0.05, FDR P < 0.1).