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. 2021 May 18;16:3457–3472. doi: 10.2147/IJN.S306269

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© 2021 Zhang et al.

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(A) Relative viabilities of HaCaT cells and A375 cells after being incubated with various concentrations of MSN(Mn)-ICG for 24 h; (B) relative viabilities of A375 cells after being incubated with DTIC, MSN(Mn)-ICG, and MSN(Mn)-ICG/DTIC with/without laser irradiation at different power densities (808 nm; 0.2, 0.4, 0.6, and 0.8 W/cm², 20min); (C) cell apoptosis and necrosis was analyzed via PI and annexin V-FITC staining when A375 cells were treated with DTIC, MSN(Mn)-ICG, and MSN(Mn)-ICG/DTIC with/without laser irradiation (808 nm, 0.75 W/cm², 10 min).