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. 2021 Mar 12;11(5):1158–1174. doi: 10.1016/j.apsb.2021.03.013

Table 5.

Stimulus-responsive drug delivery systems.

Stimulus Responsive unit Delivery strategy Drug Ref.
Image 1 Image 2 PEG-based micelles Dexamethasone 19
Image 3 mPEG-PPF micelles Ibuprofen 113
Image 4 AKP-Dex nanoparticles Dexamethasone 114
Calcium phosphate MP-HA nanoparticles Methotrexate 94
Image 5 Triglycerol monostearate DSPE-PEG/TGMS nanoparticles Dexamethasone 115
βIG-H3 derivatives – YH18 peptide/dhfas-1 116
Image 6 Manganese ferrite and ceria MFC-MSNs nanoparticles Methotrexate 117
Image 7 TPP@PMM micelles Prednisolone 118
Image 8 TPP@PMM micelles Prednisolone 118
-Se-Se- VES-PLGA-Se-Se-mPEG micelles Berberine 119
Image 9 Oxi-αCD nanoparticles Dexamethasone 120
Image 10 Fe Fe-EC nanoparticles Diclofenac sodium 121
Fe PSS-doped CaCO3 microcapsules Prednisolone 122

PPF, polypropylene fumarate; AKP, acetone-based ketal-linked prodrugs; MP, mineralization of PEGylated; TGMS, triglycerol monostearate; MFC-MSNs, manganese ferrite and ceria nanoparticle-anchored mesoporous silica nanoparticles; TPP, two-photon prednisolone; PMM, PMPC (2-methacryloyloxyethyl phosphorylcholine)−PMEMA (2-(methylthio) ethanol methacrylate); VES, vitamin E succinate; Oxi-αCD, oxygen species α-cyclodextrin; EC, ethylcellulose; PSS, poly(sodium 4-styrenesulfonate).