Figure 6.

(A) Blood glucose versus elapsed time of treatment with insulin-Au NCs and humulin R in Wistar rats. Fluorescence quenching of insulin-Au NCs by brain homogenate, which is inhibited by racecadotril and thiorphan. Reprinted with permission from Ref. 119. Copyright © 2011, John Wiley & Sons Ltd. (B) The structure of the gold cluster-TrxR1 complex. TrxR1 activity is suppressed in a dose-dependent manner by serial doses of Au₂₅Peptide₉. Scale bar = 10 μm. Reprinted with permission from Ref. 105. Copyright © 2014, American Chemical Society. (C) Au₅ but not Au₂₂ suppressed tumor growth via mitochondria target and triggered cell apoptosis in vitro/in vivo. Reprinted with permission from Ref. 167. Copyright © 2018, American Chemical Society. (D) Schematic representation of the assessment of the antitumor capability of Au-BSA, DOX, Au-DOX, and Au-Met-DOX in MCF-7 tumor cells. Reprinted with permission from Ref. 170. Copyright © 2012, Elsevier.