Table 15.

Addition reaction of arylboronic acids to various 4-oxo-3,4-dihydropyridine-1(2H)-carboxylates catalysed by Pd-NHC complexes PdL7a–c [45].

entry	R	Ar	catalyst	yield (%)	ee (%)
1	Bn	Ph	PdL7a	86	99
2	Bn	Ph	PdL7b	88	>99
3	Bn	Ph	PdL7c	88	>99
4	Bn	4-Me-C6H4	PdL7b	85	96
5	Bn	4-Me-C6H4	PdL7c	82	95
6	Bn	3-Me-C6H4	PdL7b	80	95
7	Bn	3-Me-C6H4	PdL7c	80	98
8	Bn	4-MeO-C6H4	PdL7b	78	>99
9	Bn	4-MeO-C6H4	PdL7c	82	>99
10	Bn	3-MeO-C6H4	PdL7b	76	99
11	Bn	3-MeO-C6H4	PdL7c	72	90
12	Bn	2-naphthyl	PdL7b	85	98
13	Bn	2-naphthyl	PdL7c	86	97
14	Bn	4-Ph-C6H4	PdL7b	94	97
15	Bn	4-Ph-C6H4	PdL7c	96	98
16	Et	Ph	PdL7b	92	87
17	Et	Ph	PdL7c	90	98
18	Et	2-naphthyl	PdL7b	85	97
19	Et	4-Ph-C6H4	PdL7b	95	97
20	t-Bu	Ph	PdL7b	82	99
21	t-Bu	Ph	PdL7c	80	98
22	t-Bu	2-naphthyl	PdL7b	80	97
23	t-Bu	4-Ph-C6H4	PdL7b	95	>99