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. 2021 May 10;17:1048–1085. doi: 10.3762/bjoc.17.84

Table 26.

Addition reactions of arylboronic acids to 3-alkyl-2-cyclopentenones catalysed by L9/Pd(TFA)2 [53].

graphic file with name Beilstein_J_Org_Chem-17-1048-i026.jpg
entry R Ar temp. (°C) conditions yield (%) ee (%)
1 Et Ph 25 A 95 94
2 Et 4-Me-C6H4 25 B 67 91
3 Et 4-MeO-C6H4 25 A 49 84
4 Et 4-MeO-C6H4 60 B 63 74
5 Et 4-Bu-C6H4 60 B 91 84
6 Et 4-Cl-C6H4 60 B 78 93
7 Et 4-F-C6H4 60 B 84 92
8 Et 4-CF3-C6H4 25 A 6 95
9 Et 4-CF3-C6H4 60 B 99 94
10 Et 4-MeOOC-C6H4 60 B 99 94
11 Et 3-Me-C6H4 60 B 97 91
12 Bu Ph 25 A 82 96
13 Cy Ph 60 A 91 96
14 (CH2)2COOMe Ph 60 A 86 97