Table 29.
Polystyrene-supported Pd complex PdL11 as catalyst for addition reactions of arylboronic acids to cyclic enones [57].
 | ||||
| entry | n | Ar | conversion (%) | ee (%) |
| 1 | 1 | Ph | 93 | 89 |
| 2 | 1 | 4-Me-C6H4 | 94 | 75 |
| 3 | 1 | 4-CF3-C6H4 | 85a | 91 |
| 4 | 1 | 4-Cl-C6H4 | 78a | 91 |
| 5 | 1 | 4-Ac-C6H4 | 52a | 90 |
| 6 | 1 | 4-BnO-C6H4 | 59a | 58 |
| 7 | 0 | Ph | 99 | 79 |
| 8 | 0 | 4-Me-C6H4 | 92a (96 h)/99b | 67/77b |
| 9 | 0 | 4-MeOOC-C6H4 | 99a (96 h)/99b | 90/89b |
| 10 | 0 | 3-MeOOC-C6H4 | 91a (72 h)/99b | 91/96b |
a30 mol % NH4PF6; bhomogenous conditions: 5 mol % Pd(TFA)2, 6 mol % L9, 5 equiv H2O, 60 °C, 24 h, DCE.