TABLE 1.
Results of changepoint analysis describing the dynamics for every bacterium in each mouse. ‘Response’ indicates a change from the pre-treatment level, while a ‘recovery’ marks a subsequent change in the opposite direction. Arrow indicates the direction of the response relative to the pre-treatment level.
| Response/Recovery | ||||||||
|---|---|---|---|---|---|---|---|---|
| Bacterial species | Strain ID | Mouse I | Mouse II | Mouse III | Mouse IV | Mouse V | Mouse VI | Mean |
| Akkermansia muciniphila | DSM 22959 | 2/2 (↑) | 1/1 (↑) | 1/1 (↑) | 1/0 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) |
| Bacteroides fragilis | ATCC 25285 | 1/1 (↑) | 1/1 (↓) | 1/1 (↑) | 1/1 (↓) | 1/0 (↑) | 1/1 (↑) | 1/1 (↑) |
| Bacteroides ovatus | ATCC 8483 | 2/2 (↓) | 1/1 (↓) | 1/1 (↓) | 1/0 (↓) | 1/0 (↓) | 2/2 (↓) | 1/0 (↓) |
| Bacteroides vulgatus | ATCC 8482 | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) |
| Clostridium hiranonis | DSM 13275 | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) |
| Clostridium ramosum | DSM 1402 | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) |
| Enterococcus faecalis | ATCC 29200 | 1/1 (↑) | 1/0 (↑) | 1/1 (↑) | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) | 1/1 (↑) |
| Escherichia coli | MG1655 | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/0 (↓) | 1/1 (↑) |
| Klebsiella oxytoca | ATCC 700324 | 1/0 (↑) | 1/1 (↑) | 1/0 (↑) | 1/0 (↑) | 1/1 (↑) | 1/0 (↑) | 1/0 (↑) |
| Lactobacillus reuteri | DSM 20016 | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 1/1 (↑) | 2/2 (↑) | 1/1 (↑) |
| Parabacteroides distasonis | ATCC 8503 | 1/1 (↑) | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) |
| Proteus mirabilis | ATCC 29906 | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) | 1/0 (↑) | 2/2 (↑) | 1/0 (↑) | 1/0 (↑) |