Table 2. Factors Associated With Results Reporting in the Multivariable Analysis.
| Characteristic | Adjusted HR (95% CI) | P value |
|---|---|---|
| Primary completion year | ||
| Per year increase | 1.11 (1.10-1.13) | <.001 |
| Registration before participant enrollment | ||
| No | 1 [Reference] | |
| Yes | 1.31 (1.24-1.38) | <.001 |
| Phase | ||
| 0-1 | 1 [Reference] | |
| 1/2-2 | 2.55 (2.39-2.72) | <.001 |
| 2/3-3 | 2.71 (2.44-3.00) | <.001 |
| 4 | 1.94 (1.66-2.26) | <.001 |
| NAa | 1.82 (1.63-2.03) | <.001 |
| No. of groups | ||
| 1 | 1 [Reference] | |
| 2 | 1.18 (1.08-1.28) | .001 |
| ≥3 | 1.02 (0.93-1.12) | .72 |
| Treatment randomization | ||
| Nonrandomized | 1 [Reference] | |
| Randomized | 0.78 (0.72-0.85) | <.001 |
| Total enrollment, No. of patients | ||
| ≤50 | 1 [Reference] | |
| 51-100 | 1.17 (1.09-1.24) | <.001 |
| >100 | 1.43 (1.33-1.54) | <.001 |
| Funding source | ||
| Industry | 1 [Reference] | |
| NIH | 1.39 (1.29-1.49) | <.001 |
| Other academic or nonprofit organizations | 0.66 (0.62-0.70) | <.001 |
| Recruitment status | ||
| Completed | 1 [Reference] | |
| Terminated | 0.88 (0.83-0.93) | <.001 |
Abbreviations: HR, hazard ratio; NA, not applicable; NIH, National Institutes of Health.
a
Including trials of devices and behavioral interventions.