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Effect of HTT priming in FD-stimulated HaCaT keratinocyte preconditioned media on ECM degradation by integrated HDFs. (A) MMP and TIMP expression was evaluated by RT-PCR analysis. The activity of collagenase (B) and elastase (C) was evaluated in cell lysates. All experiments were carried out in triplicates (n = 3) and indicated as means ± SD. “*” and “**” respectively denote p < 0.05 and p < 0.01 if they are significantly different from those of HPM-FD treated HDFs “#”.
