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Nrf2-keap1 signaling pathway simplified diagram of the downstream effects of nuclear translocation. ARE, antioxidant response element; HO-1, heme oxygenase-1; Keap1, Kelch-like ECH-associated protein 1; NQO1, NAD(P)H: quinone oxidoreductase 1; Nrf2, nuclear factor erythroid 2-related factor 2; SOD, superoxide dismutase.
