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. 2021 Apr 29;11(5):654. doi: 10.3390/biom11050654

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Peroxiredoxin 2 (Prx2) alters the number and location of major histocompatibility complex class II (OX-6) positive (+) cells at the choroid plexus (CP). (a) Examples of OX-6 immunohistochemistry at the choroid plexus one day after intracerebroventricular (icv) saline injection; (b) Examples of OX-6 immunohistochemistry at the choroid plexus one day after icv Prx2 injection. Note the intense staining of apical epiplexus cells after Prx2 injection; (c) The numbers of OX-6 positive cells in saline- and Prx2-injected animals were quantified and expressed as a % of all CP cells; (d) The numbers of OX-6 positive epiplexus cells in the two groups were also analyzed. Values are means; n = 6; * p < 0.05 vs. saline group; # p < 0.01 vs. saline group. Scale bar = 50 μm at low magnification, 20 μm at high magnification. Dots represent data for each animal.