Table 4.
The potential of six individual polyphenols at 0.1 and 1 mg/mL towards the inhibition (%) of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities.
| Standards | AChE % Inhibition | BChE % Inhibition | ||
|---|---|---|---|---|
| 0.1 mg/mL | 1 mg/mL | 0.1 mg/mL | 1 mg/mL | |
| Ferulic A. | 1.0 ± 0.9 b | 15.4 ± 0.1 a b | 14.6 ± 1 a b | 27.2 ± 0.9 a b |
| p-Coumaric A. | 5.2 ± 0.4 a | 14.4 ± 0.5 b c | 6.4 ± 0.6 b | 22.1 ± 1.3 b c |
| Catechin | 3.8 ± 1.1 ab | 14.9 ± 0.2 a b | 12.2 ± 0.6 a b | 31.6 ± 0.4 a b |
| 4-Hydroxybenzoic A. | 1.0 ± 0.2 b | 5.2 ± 0.9 c | n.d. | 11.9 ± 0.6 b c |
| Caffeic A. | 3.3 ± 0.4 a b | 25.5 ± 0.2 a | 15.4 ± 1.3a | 52.3 ± 0.8 a |
| Protocatechuic A. | n.d. | 13.8 ± 0.7 b c | n.d. | 7.6 ± 2.4 c |
| Blends |
TPC
μgGAE/mg |
SQP
μg/mg |
AChE
%Inhibition |
BChE
%Inhibition |
| FP EtOAc1 | 260.6 ± 11.9 a b | 1000 | n.d. | 16.7 ± 1.5 a |
| BP DE1 | 243.8 ± 1.4 b | 1000 | 11.1 ± 0.6 a | 9.9 ± 0.2 b |
| BP EtOAc3 | 267.4 ± 8.4 a | 1000 | 8.3 ± 0.1 a | 11.2 ± 1.1 a b |
Three blends (FP EtOAc1, BP DE1, BP EtOAc3), that mimic the polyphenol content in the BSG fractions with the highest Total phenolic content (TPC) and sum of quantified polyphenols (SQP) were tested as well. The values reported for each AChE and BChE at specific concentrations with their individual polyphenols bearing different letters (a, b, c) are significantly different (p < 0.05) from each other. n.d. = not detected.