Figure 6.

Calcein release from phase changeable droplet-liposome clusters (PDLCs) after 5 and 10 min of sonication (A) schematic illustration of the acoustic chamber setup used for measuring calcein release from PDLCs. (B) vaporization acoustic signals during and after vaporization used for visualizing the completion of droplet vaporization. (C) Effect of sonication and temperature on release from liposomes alone (no droplets). Only sonication at 45 °C showed a statistically significant release above zero (* p < 0.05). (D) Calcein release following US exposure. Release from PDLCs was significantly higher than any other group after 10 min (* p < 0.05). Release after 5 min was higher than the negative controls but not significantly. N = 3 per group.