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. 2021 May 24;325(23):2397–2399. doi: 10.1001/jama.2021.8246

Table. Changes in COVID-19 Vaccine Hesitancy and Public Trust in Vaccination Between October 14, 2020, and March 29, 2021, in the Understanding America Study.

Demographic characteristic COVID-19 vaccine hesitancy, % (95% CI)a,b Public trust in vaccination, mean (95% CI)c,d
Survey wave Change in hesitancy by March 2021 Survey wave Change in trust by March 2021
October 2020 (n = 6016) March 2021 (n = 6035) October 2020 (n = 6016) March 2021 (n = 6035)
Overall sample 46.0 (44.2 to 47.7) 35.2 (33.4 to 36.9) −10.8 (−12.7 to −8.9) 2.6 (2.5 to 2.6) 3.0 (2.9 to 3.0) 0.4 (0.3 to 0.5)
Age, y
18-39 50.7 (47.5 to 53.8) 44.1 (40.8 to 47.3) −6.6 (−10.1 to −3.2) 2.4 (2.3 to 2.5) 2.7 (2.6 to 2.9) 0.3 (0.2 to 0.5)
40-59 49.7 (46.8 to 52.6) 38.6 (35.6 to 41.6) −11.1 (−14.2 to −8.0) 2.4 (2.3 to 2.5) 2.8 (2.6 to 2.9) 0.3 (0.2 to 0.4)
≥60 36.2 (33.5 to 39.0) 21.0 (18.6 to 23.4) −15.2 (−18.1 to −12.4) 3.0 (2.9 to 3.1) 3.5 (3.4 to 3.6) 0.5 (0.4 to 0.6)
Sex
Men 39.9 (37.3 to 42.4) 30.7 (28.2 to 33.2) −9.3 (−11.9 to −6.4) 2.8 (2.7 to 2.9) 3.2 (3.1 to 3.3) 0.4 (0.3 to 0.5)
Women 51.8 (49.4 to 54.1) 39.4 (37.0 to 41.8) −12.4 (−15.0 to −9.7) 2.3 (2.3 to 2.4) 2.7 (2.6 to 2.8) 0.4 (0.3 to 0.5)
Race/ethnicity
White 42.4 (40.4 to 44.3) 34.8 (32.8 to 36.8) −7.6 (−9.6 to −5.5) 2.8 (2.7 to 2.8) 3.1 (3.0 to 3.1) 0.3 (0.2 to 0.4)
Hispanic 52.3 (47.0 to 57.5) 36.4 (31.2 to 41.7) −15.8 (−21.8 to −9.8) 2.4 (2.2 to 2.6) 3.0 (2.7 to 3.2) 0.6 (0.4 to 0.8)
Black 63.9 (58.7 to 69.2) 43.0 (37.3 to 48.7) −20.9 (−27.2 to −14.6) 1.7 (1.5 to 1.8) 2.3 (2.1 to 2.5) 0.6 (0.4 to 0.8)
Othere 33.7 (26.7 to 40.8) 20.4 (14.3 to 26.6) −13.3 (−20.9 to −5.8) 3.0 (2.8 to 3.2) 3.5 (3.2 to 3.8) 0.5 (0.2 to 0.7)
College degree
No 54.6 (52.3 to 56.8) 42.9 (40.6 to 45.2) −11.7 (−14.2 to −9.1) 2.3 (2.2 to 2.4) 2.5 (2.5 to 2.6) 0.2 (0.2 to 0.3)
Yes 30.5 (27.9 to 33.0) 20.9 (18.6 to 23.2) −9.6 (−12.1 to −7.1) 3.1 (3.0 to 3.2) 3.8 (3.7 to 3.9) 0.7 (0.6 to 0.8)
Income, $
<50 000 54.0 (51.3 to 56.6) 43.7 (40.9 to 46.4) −10.3 (−13.3 to −7.3) 2.2 (2.1 to 2.3) 2.5 (2.4 to 2.6) 0.3 (0.2 to 0.4)
≥50 000 39.7 (37.5 to 41.9) 28.2 (26.1 to 30.4) −11.5 (−13.8 to −9.1) 2.9 (2.8 to 3.0) 3.4 (3.3 to 3.5) 0.5 (0.4 to 0.6)
a

Vaccine hesitancy is defined as being unsure or somewhat or very unlikely to be vaccinated against COVID-19.

b

Estimates are derived from predicted probabilities calculated after logistic regression with cluster robust SEs.

c

Public trust in vaccination ranged from 0 (do not trust development/approval processes) to 6 (fully trust development/approval processes).

d

Estimates are from linear regression with cluster robust SEs.

e

Race/ethnicity was self-reported by panel members. The other race/ethnicity group includes Asian, American Indian/Alaska Native, and Native Hawaiian orother Pacific Islander, which were combined owing to small group sizes.