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. 2021 Apr 28;9(5):483. doi: 10.3390/biomedicines9050483

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Multispectral optoacoustic tomography (MSOT) of intestinal inflammation using hemoglobin as a surrogate for disease activity. The technique enables hybrid imaging together with B-mode ultrasound imaging (RUCT). (A) MSOT imaging of the liver in humans enabling the generation of signals for different subcellular compounds; (B) S = serosa, M = muscularis mucosa, Sm = submucosa, Mu = mucosa, L = lumen, RUCT = reflectance ultrasound computed tomography. Figure (A) reproduced and modified from [131]. (https://creativecommons.org/licenses/by/4.0/ (accessed on 9 April 2021)).