Skip to main content
. 2021 Apr 27;8(5):51. doi: 10.3390/bioengineering8050051

Figure 3.

Figure 3

SMC insoluble elastin and collagen deposition in both discs and strands are increased after 30 days of CM or EV treatment, but not dCM. All fibrin constructs were cultured as in Figure 2. (A) Insoluble elastin deposition by Scheme 30. days of stimulation with CM, EV×1, and EV×3 relative to the negative control, nCM. (B) Total collagen deposition by SMCs in fibrin discs was increased after 30 days of stimulation with 3×EV relative to nCM. (C) Insoluble elastin deposition by SMCs in fibrin strands was increased after 30 days of stimulation with 3×EV relative to nCM. (D) Total collagen deposition by SMCs in fibrin strands was increased after 30 days of stimulation with CM, EV×1, and EV×3 relative to nCM. Sample size is indicated for each group. * = p < 0.05 relative to nCM.