[Ca2+]c	concentration of intracellular free calcium ion
2APB	2-aminoethoxydiphenyl borate
ACA	N-(p-amylcinnamoyl)anthranilic acid
ADPR	ADP-ribose
AMD	age-related macular degeneration
ARPE19	adult retinal pigment epithelial 19
Casp -3	caspase -3
Casp -9	caspase -9
Ca2+	calcium ion
CRISPR	clustered regularly interspaced short palindromic repeats
fROS	free reactive oxygen species
GSH	glutathione
GSHPx	glutathione peroxidase
h-RPE	human retinal pigment epithelium
MDA	malondialdehyde
mMDP	mitochondrial membrane depolarization
mPTP	mitochondrial permeability transition pore
rGSH	reduced glutathione
TRP	transient receptor potential
TRPM2	transient receptor potential melastatin 2
TSPO	18 kDa mitochondrial translocator protein
VDCC	anion protein of voltage-dependent channel