| [Ca2+]c | concentration of intracellular free calcium ion |
| 2APB | 2-aminoethoxydiphenyl borate |
| ACA | N-(p-amylcinnamoyl)anthranilic acid |
| ADPR | ADP-ribose |
| AMD | age-related macular degeneration |
| ARPE19 | adult retinal pigment epithelial 19 |
| Casp -3 | caspase -3 |
| Casp -9 | caspase -9 |
| Ca2+ | calcium ion |
| CRISPR | clustered regularly interspaced short palindromic repeats |
| fROS | free reactive oxygen species |
| GSH | glutathione |
| GSHPx | glutathione peroxidase |
| h-RPE | human retinal pigment epithelium |
| MDA | malondialdehyde |
| mMDP | mitochondrial membrane depolarization |
| mPTP | mitochondrial permeability transition pore |
| rGSH | reduced glutathione |
| TRP | transient receptor potential |
| TRPM2 | transient receptor potential melastatin 2 |
| TSPO | 18 kDa mitochondrial translocator protein |
| VDCC | anion protein of voltage-dependent channel |
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