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Changes in the circRNA expression profiles in the spinal cord of the DNP mice. (A) Heat map of the circRNAs with hierarchical clustering of the differentially expressed mRNAs between the mice in the D and N groups. In the clustering analysis, up- and downregulated genes are colored in red and blue, respectively. (B) Volcano plot displaying the up- and downregulated circRNAs between the D and N groups. D, diabetic; N, normal control; DNP, diabetic neuropathy; circRNA, circular RNA.
