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. 2021 Apr 22;10(5):981. doi: 10.3390/cells10050981

Figure 1.

Figure 1

Diagrammatic representation of Leucine Rich repeat Kinase 2 (LRRK2). Depicted are the functional domains of LRRK2. Different variants are indicated in different colors, including pathogenic variants (red), rare variants potentially pathogenic (purple), and protective variants (green). ARM, armadillo repeat domain; ANK, ankyrin repeat domain; LRR, leucine-rich repeat domain; ROC, Ras of complex proteins domain; COR, C-terminal of ROC domain; KIN, kinase domain; WD40, WD40 repeat domain.