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. 2021 Apr 23;10(5):650. doi: 10.3390/antiox10050650

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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OLE dietary treatment induced up-regulation of Nrf-2/HO-1 protein expression in hind paws homogenates. Densitometry analysis was normalized with respect to β-actin (house-keeping). Western blot images are representative of separate experiments with similar results. Naïve group, non-arthritic control animals fed with SD; CIA, control group induced arthritic animals fed with SD; OLE induced arthritic animals fed with OLE enriched diet (0.025% w/w). Values represented mean ± S.E.M. (n = 8), ⁺ p < 0.05 vs. Naïve control group; * p < 0.05; *** p < 0.001 vs. CIA group.