Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 27;10(5):1027. doi: 10.3390/cells10051027

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Histoarchitectonics and immunophenotype of CTLA-4(+) tonsillar cells stained with antibodies of the SP355 clone. (a) Predominant localization of CTLA-4(+) in the extrafollicular regions of the tonsil. (b) Location of CTLA-4(+) cells in the germinal center of the lymphatic follicle and in the perifollicular zone. (c–c″) Cells with moderate (tryptase) and high levels of CTLA-4 expression. (d) Two CTLA-4(+) cells, one of which expresses CD68. (e) CTLA-4(+) cells are in contact with type 1 macrophage (presumably). (f) CTLA-4(+) cells contacting CD3+, lack of co-expression. (g) CTLA-4(+) cell surrounded by CD4+ cells. (h–h″) Co-expression of CD4 and CTLA-4. (i–i″) Co-localization of CTLA-4 and CD38 (plasma cell). Scale bar 125 µm for (a,b), and 10 µm for the rest.