Table 1.
Demographic data of healthy volunteers at enrollment (n = 20).
| Parameter | Gender | p-Value | Total (n = 20) | |
|---|---|---|---|---|
| Women (n = 9) | Men (n = 11) | |||
| Age (years) | ||||
| Mean [95% CI] | 43 [39, 48] | 54 [49, 58] | 0.002 | 49 [45, 53] |
| Age n (%) | ||||
| ≤50 | 8 (89) | 4 (36) | NS | 12 (60) |
| 51–55 | 1 (11) | 3 (27) | 4 (20) | |
| 56–60 | 0 (0) | 3 (27) | 3 (15) | |
| 61–65 | 0 (0) | 1 (9) | 1 (5) | |
| ≥66 | 0 (0) | 0 (0) | 0 (0) | |
| Height (m) | ||||
| Mean [95% CI] | 1.68 [1.62, 1.74] | 1.76 [1.73, 1.79] | 0.005 | 1.73 [1.69, 1.76] |
| Weight (kg) | ||||
| Mean [95% CI] | 68 [61, 75] | 87 [79, 95] | <0.001 | 79 [72, 85] |
| Waist circumference (cm) | ||||
| Mean [95% CI] | 88 [82, 94] | 102 [96, 108] | 0.001 | 96 [90, 101] |
| BMI (kg/m2) | ||||
| Mean [95% CI] | 24 [22, 25] | 28 [26, 30] | 0.004 | 26 [25, 28] |
| BMI n (%) | ||||
| 18.5–24—Healthy weight | 5 (56) | 1 (9) | 0.031 | 6 (30) |
| 25–29—Overweight | 4 (44) | 6 (55) | 10 (50) | |
| 30–34—Class I Obesity | 0 (0) | 4 (36) | 4 (20) | |
| Smoke n (%) | ||||
| Yes | 2 (22) | 1 (9) | NS | 3 (155) |
| No | 6 (67) | 10 (91) | 16 (80) | |
| ex-smokers | 1 (11) | 0 (0) | 1 (0.05) | |
| Systolic Blood Pressure (mmHg) | ||||
| Mean [95% CI] | 112 [102, 121] | 129 [121, 137] | 0.004 | 121 [114, 128] |
| Diastolic Blood Pressure (mmHg) | ||||
| Mean [95% CI] | 66 [59, 71] | 81 [75, 87] | <0.001 | 74 [69, 80] |