Figure 5.

Oxygen consumption rate (OCR) in both CSC populations treated for two (a,b) or five weeks (c). HTLA-CSCs and ER-CSCs were treated three times a week with 0.1 µM C2-4, with 5 µM SSZ or with 1.25 µM Etoposide, administered once a week alone or in combination with C2-4 or SSZ. Results were reported as nmol O/min/10⁶ cells. Bar graph summarizes quantitative data of means ± S.E.M. of three independent experiments. ** p < 0.01 vs. untreated CSCs (Ctr); ^## p < 0.01 vs. Etoposide-treated CSCs.