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. 2021 May 20;15:11782234211015753. doi: 10.1177/11782234211015753

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Reduction in growth rate of MDA-MB-468 cells expressing GRK4 shRNA 167 treated with various concentrations of doxycycline for 15 days in total. (A) growth rate; (B) Cell counts at the end of experiment. Cell growth was expressed as fold increase compared with the number on day 1 of each treatment (Mean ± SD, n = 4). *P < .005, **P < .001, ***P < .0001 compared with vehicle control. The experiment was repeated four times with different length of doxycycline treatment. The results were consistent (S5 Figure). Shown here is a representative result.