Table 1.
Biological activities of sulfated steroids.
| No. | Antitumor & Related Activity, (Pa) * | Violation of Lipid Metabolism, (Pa )* | Additional Predicted Activity, (Pa) * |
|---|---|---|---|
| 1 | Antineoplastic (0.887) Chemopreventive (0.815) |
Anti-hypercholesterolemic (0.901) Cholesterol synthesis inhibitor (0.822) |
Hemostatic (0.931) Biliary tract disorders treatment (0.814) |
| 2 | Antineoplastic (0.906) Chemopreventive (0.816) |
Anti-hypercholesterolemic (0.895) Cholesterol synthesis inhibitor (0.816) |
Hemostatic (0.927) Biliary tract disorders treatment (0.819) |
| 3 | Antineoplastic (0.828) Chemopreventive (0.735) Apoptosis agonist (0.703) |
Atherosclerosis treatment (0.786) Cholesterol synthesis inhibitor (0.733) Anti-hypercholesterolemic (0.711) |
Hepatoprotectant (0.832) Anti-inflammatory (0.807) Biliary tract disorders treatment (0.717) |
| 4 | Antineoplastic (0.778) Chemopreventive (0.802) |
Cholesterol synthesis inhibitor (0.762) Atherosclerosis treatment (0.744) |
Biliary tract disorders treatment (0.752) Anti-ischemic, cerebral (0.774) |
| 5 | Chemopreventive (0.843) Antineoplastic (0.804) |
Atherosclerosis treatment (0.721) Cholesterol synthesis inhibitor (0.744) |
Biliary tract disorders treatment (0.713) Wound-healing agent (0.831) |
| 6 | Antineoplastic (0.880) Apoptosis agonist (0.865) |
Cholesterol synthesis inhibitor (0.774) Anti-hypercholesterolemic (0.821) |
Wound-healing agent (0.866) Biliary tract disorders treatment (0.764) |
| 7 | Antineoplastic (0.877) Chemopreventive (0.722) Apoptosis agonist (0.712) |
Cholesterol synthesis inhibitor (0.776) Cholesterol synthesis inhibitor (0.755) Anti-hypercholesterolemic (0.732) |
Wound-healing agent (0.852) Hemostatic (0.757) Biliary tract disorders treatment (0.741) |
| 8 | Chemopreventive (0.857) Antineoplastic (0.765) |
Anti-hypercholesterolemic (0.884) Cholesterol synthesis inhibitor (0.766) |
Biliary tract disorders treatment (0.871) Hemostatic (0.736) |
| 9 | Antineoplastic (0.904) Chemopreventive (0.843) Apoptosis agonist (0.721) |
Atherosclerosis treatment (0.889) Cholesterol synthesis inhibitor (0.821) Anti-hypercholesterolemic (0.820) |
Biliary tract disorders treatment (0.911) Anti-inflammatory (0.821) Biliary tract disorders treatment (0.724) |
| 10 | Chemopreventive (0.879) Apoptosis agonist (0.850) Antineoplastic (0.824) |
Cholesterol synthesis inhibitor (0.862) Atherosclerosis treatment (0.862) Anti-hypercholesterolemic (0.812) |
Wound-healing agent (0.872) Biliary tract disorders treatment (0.753) Hemostatic (0.731) |
| 11 | Chemopreventive (0.882) Antineoplastic (0.773) Apoptosis agonist (0.748) |
Cholesterol synthesis inhibitor (0.869) Atherosclerosis treatment (0.858) Anti-hypercholesterolemic (0.823) |
Biliary tract disorders treatment (0.762) Hemostatic (0.739) |
| 12 | Chemopreventive (0.873) Antineoplastic (0.778) Apoptosis agonist (0.751) |
Cholesterol synthesis inhibitor (0.861) Atherosclerosis treatment (0.844) Anti-hypercholesterolemic (0.832) |
Biliary tract disorders treatment (0.812) Wound-healing agent (0.775) |
| 13 | Antineoplastic (0.902) Chemopreventive (0.878) |
Cholesterol synthesis inhibitor (0.855) Anti-hypercholesterolemic (0.831) |
Wound-healing agent (0.884) |
* Only activities with Pa > 0.5 are shown.