Table 2.
Biological activities of mono sulfated steroids.
| No. | Antitumor & Related Activity, (Pa) * | Violation of Lipid Metabolism, (Pa) * | Additional Predicted Activity, (Pa) * |
|---|---|---|---|
| 14 | Chemopreventive (0.828) Antineoplastic (0.798) |
Anti-hypercholesterolemic (0.919) Cholesterol synthesis inhibitor (0.803) |
Wound-healing agent (0.975) Biliary tract disorders treatment (0.861) |
| 15 | Antineoplastic (0.780) Chemopreventive (0.766) |
Anti-hypercholesterolemic (0.874) Cholesterol synthesis inhibitor (0.789) |
Biliary tract disorders treatment (0.955) Wound-healing agent (0.945) |
| 16 | Chemopreventive (0.841) Antineoplastic (0.804) Prostate disorders treatment (0.675) |
Anti-hypercholesterolemic (0.907) Cholesterol synthesis inhibitor (0.818) Atherosclerosis treatment (0.724) |
Wound-healing agent (0.846) Biliary tract disorders treatment (0.823) Hepatoprotectant (0.816) |
| 17 | Antineoplastic (0.858) Chemopreventive (0.797) Apoptosis agonist (0.719) |
Anti-hypercholesterolemic (0.886) Cholesterol synthesis inhibitor (0.753) Atherosclerosis treatment (0.699) |
Biliary tract disorders treatment (0.801) Wound-healing agent (0.783) Hepatoprotectant (0.771) |
| 18 | Antineoplastic (0.791) Prostate disorders treatment (0.692) |
Anti-hypercholesterolemic (0.909); Cholesterol synthesis inhibitor (0.806); |
Wound-healing agent (0.938) Biliary tract disorders treatment (0.850) |
| 19 | Chemopreventive (0.887) Antineoplastic (0.803) |
Anti-hypercholesterolemic (0.940) Cholesterol synthesis inhibitor (0.815); |
Wound-healing agent (0.952) Hepatoprotectant (0.876) |
| 20 | Chemopreventive (0.828) Antineoplastic (0.798) |
Anti-hypercholesterolemic (0.919); Cholesterol synthesis inhibitor (0.803) |
Wound-healing agent (0.975) Biliary tract disorders treatment (0.861) |
| 21 | Chemopreventive (0.934) Antineoplastic (0.867) Apoptosis agonist (0.857) |
Anti-hypercholesterolemic (0.912) Atherosclerosis treatment (0.776) Cholesterol synthesis inhibitor (0.750) |
Hemostatic (0.928) Biliary tract disorders treatment (0.764) Wound-healing agent (0.727) |
| 22 | Chemopreventive (0.891) Antineoplastic (0.791) |
Anti-hypercholesterolemic (0.789) Cholesterol synthesis inhibitor (0.788); |
Wound-healing agent (0.816) Biliary tract disorders treatment (0.807) |
| 23 | Antineoplastic (0.822) Chemopreventive (0.806) |
Anti-hypercholesterolemic (0.926) Atherosclerosis treatment (0.804) |
Biliary tract disorders treatment (0.879); Hepatoprotectant (0.764) |
| 24 | Antineoplastic (0.781) Chemopreventive (0.780) |
Anti-hypercholesterolemic (0.929); Cholesterol synthesis inhibitor (0.762) |
Biliary tract disorders treatment (0.910); Hepatoprotectant (0.876) |
| 25 | Chemopreventive (0.837) Antineoplastic (0.777) |
Acute neurologic disorders treatment (0.808) Cholesterol synthesis inhibitor (0.719); |
Wound-healing agent (0.895) Hepatoprotectant (0.888); |
| 26 | Chemopreventive (0.902) Apoptosis agonist (0.894) Antineoplastic (0.866); |
Anti-hypercholesterolemic (0.931) Atherosclerosis treatment (0.807) Cholesterol synthesis inhibitor (0.732) |
Biliary tract disorders treatment (0.844) Hepatic disorders treatment (0.818) Wound-healing agent (0.556); |
| 27 | Chemopreventive (0.850) Antineoplastic (0.777) |
Anti-hypercholesterolemic (0.897); Cholesterol synthesis inhibitor (0.819); |
Hepatoprotectant (0.879) Biliary tract disorders treatment (0.866) |
| 28 | Chemopreventive (0.944) Apoptosis agonist (0.808) |
Cholesterol synthesis inhibitor (0.714); Atherosclerosis treatment (0.708); |
Hepatoprotectant (0.872) Antifungal (0.831) |
| 29 | Chemopreventive (0.913) Antineoplastic (0.796) Apoptosis agonist (0.790) |
Cholesterol synthesis inhibitor (0.762) Anti-hypercholesterolemic (0.726) Atherosclerosis treatment (0.717) |
Wound-healing agent (0.965) Hepatoprotectant (0.933) Biliary tract disorders treatment (0.791); |
| 30 | Antineoplastic (0.772) Chemopreventive (0.715); |
Atherosclerosis treatment (0.611) Cholesterol synthesis inhibitor (0.550) |
Hepatoprotectant (0.893) Erythropoiesis stimulant (0.789); |
| 31 | Chemopreventive (0.882) Antineoplastic (0.803) |
Anti-hypercholesterolemic (0.906) Cholesterol synthesis inhibitor (0.823) |
Biliary tract disorders treatment (0.847) Hepatoprotectant (0.812); |
* Only activities with Pa > 0.5 are shown.