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Regulation of HuD expression. Several factors affect HuD expression. Ngn2, SATB1, IR/IRS/AKT/FoxO1, notch3, and thyroid hormone T3 regulate transcription of HuD gene. Celf1, miR–375, miR–129–5p and alternative splicing are involved in post–transcriptional and translational control of HuD mRNA. CARM1 and PKC mediate post–translational regulation of HuD protein.
