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. 2021 Apr 24;13(5):1438. doi: 10.3390/nu13051438

Table 4.

Hepatic fatty acid ratios in adult male Wistar rat offspring 1.

RC-NF HC-NF RC-HF HC-HF P GD P PWD P GD*PWD
C 16:1 n-7/C16:0 0.08 ± 0.008 0.13 ± 0.013* 0.049 ± 0.006 0.037 ± 0.003 0.07 0.01 0.01
C18:1 n-9/C18:0 0.73 ± 0.07 0.84 ± 0.09 1.63 ± 0.24 0.98 ± 0.15 * 0.09 0.01 0.02
DHA/ARA 0.36 ± 0.02 0.36 ± 0.02 1.19 ± 0.12 1.69 ± 0.06 * 0.36 0.33 0.21
DHA/EPA 22.5 ± 3.5 21.9 ± 1.8 20.4 ± 2.5 33.7 ± 6.55 0.12 0.24 0.11
n-6/n-3 4.28 ± 0.21 4.23 ± 0.22 5.43 ± 0.21 4.52 ± 0.23 ** 0.03 0.01 0.05

1 Male Wistar offspring were born to dams fed either a recommended choline (RC) or a high choline (HC) gestational diet (GD) then weaned to either a normal fat (NF) or high fat (HF) post-weaning diet (PWD) for 17 weeks. Values are mean ± SEM, n = 8–9/group. Data were analyzed using a 2-way ANOVA to test the interaction effect of GD and PWD. * p < 0.05, ** p < 0.01 by Student’s T-test comparing groups stratified by PWD. Abbreviations: RC-NF: recommended choline (1 g/kg) gestational diet weaned to normal fat (16%Kcal) post-weaning diet; HC-NF: high choline (2.5 g/kg) gestational diet weaned to normal fat (16% Kcal) post-weaning diet; RC-HF: recommended choline (1 g/kg) gestational diet weaned to high fat (45%Kcal) post-weaning diet; HC-HF: high choline (2.5 g/kg) gestational diet weaned to high fat (45%Kcal) post-weaning diet; DHA: docosahexaenoic acid; ARA: arachidonic acid; EPA: eicosapentaenoic acid; n-6: omega-6 polyunsaturated fatty acids; n-3: omega-3 polyunsaturated fatty acids.