Table 2.
Suggested reference limits for rheumatoid arthritis.
|
Included populations |
Sick populations |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Test | Sex | N | % | Lower | 90%CI | Upper | 90%CI | N | Lower | 90%CI | Upper | 90%CI | Health-associated reference interval |
|
ALP U/L |
B | 1165 | 89% | 37 | (36–39) | 181 | (158–200) | 1306 | 37 | (36–39) | 243 | (208–293) | 35–105 |
|
ALT U/L |
F | 1137 | 99% | 8 | (7-9) | 74 | (66–87) | 1145 | 8 | (7-9) | 76 | (70–91) | 10–45 |
| Albumin g/L | F | 101 | 13% | 33 | (20–36) | 47 | (47–49) | 771 | 21 | (21-23) | 46 | (46–47) | 18-39: 36–48; 40–70: 36–45; >70: 34-45 |
|
Bilirubin μmol/L |
M | 248 | 89% | 3 | (3-4) | 29 | (21–36) | 279 | 3 | (3-4) | 32 | (23–55) | 5–25 |
| F | 528 | 80% | 3 | (3-4) | 21 | (20-24) | 662 | 3 | (3-3) | 24 | (21-28) | 5–25 | |
|
CK U/L |
M | 261 | 99% | 21 | (17-25) | 386 | (289–736) | 264 | 21 | 17-25) | 386 | (289–736) | < 50: 50–400; ≥ 50: 40-280 |
| F | 680 | 100% | 17 | (15-20) | 261 | (210–326) | 682 | 17 | (15-20) | 259 | (205–326) | 35–210 | |
| CRP mg/L | M | 143 | 32% | 5 | (5-5) | 31 | (19–42) | 450 | 5 | (5-5) | 209 | (164–228) | < 5 |
| F | 213 | 19% | 5 | (5-5) | 114 | (30–127) | 1140 | 5 | (5-5) | 199 | (173–221) | < 5 | |
| Calcium mmol/L | F | 269 | 36% | 2.09 | (2.06–2.14) | 2.55 | (2.51–2.55) | 748 | 1.99 | (1.91-2.02) | 2.57 | (2.55-2.63) | 2.15–2.51 |
| Cholesterol mmol/L | F | 85 | 13% | 3.8 | (3.4–4.2) | 7.5 | (7.0–8.0) | 679 | 3 | (2.9-3.3) | 7.7 | (7.4–8.0) | <30: 2.9–6.1; 30–49: 3.3–6.9; ≥50: 3.9–7.8 |
|
Creatinine μmol/L |
M | 192 | 43% | 56 | (53–62) | 105 | (98–119) | 451 | 55 | (51–58) | 187 | (162–205) | 60–105 |
| F | 739 | 64% | 41 | (39–42) | 93 | (87–95) | 1149 | 39 | (37–41) | 145 | (130–177) | 45–90 | |
| ESR mm/h | B | 219 | 18% | 2 | (1-2) | 60 | (44–78) | 1196 | 2 | (2-2) | 92 | (85–96) |
F < 45: ≤ 14; F > 45: ≤ 24; M < 45: ≤ 7; M > 45: ≤ 17 |
|
Ferritin μg/L |
F | 889 | 99% | 15 | (14-16) | 700 | (563–822) | 896 | 15 | (14-16) | 714 | (589–867) | 20–167 |
| Folate nmol/L | F | 290 | 48% | 6 | (4-7) | 54 | (54-54) | 610 | 6 | (5-6) | 54 | (54-54) | 7–29 |
|
GT U/L |
M | 250 | 77% | 11 | (10-12) | 250 | (202–447) | 324 | 11 | (10-13) | 607 | (247–798) | < 40: 10–80; ≥ 40: 15-115 |
| F | 661 | 82% | 10 | (10-10) | 170 | (141–221) | 811 | 10 | (10-10) | 299 | (260–387) | < 40: 10–45; ≥ 40: 10-75 | |
| Hemoglobin g/dL | M | 83 | 18% | 13.2 | (12.7–13.5) | 16.6 | (16.3–16.8) | 449 | 9.7 | (9.2-10.0) | 16.7 | (16.4–16.9) | 13.4–17 |
| F | 206 | 18% | 10.8 | (10.3–11.5) | 15.2 | (15.0–15.7) | 1145 | 9.4 | (9.1-9.8) | 15.6 | (15.3–15.7) | 11.7–15.3 | |
| IgG g/L | M | 174 | 99% | 5.1 | (3.8–5.9) | 19.8 | (17.2–21.5) | 175 | 5.1 | (3.8–5.9) | 19.8 | (17.2–21.5) | 6.1–14.9 |
| F | 402 | 78% | 5.1 | (4.8–5.7) | 17.3 | (16.0–17.7) | 513 | 4.8 | (4.6–5.2) | 17.6 | (16.6–18.2) | 19-50: 6.9-15.7; > 50:6.1-14.9 | |
| Leukocytes x 109/L | M | 444 | 99% | 3.7 | (3.5–4.1) | 18.4 | (15.7–23.4) | 449 | 3.7 | (3.1–4.0) | 18.6 | (15.7–27.1) | 4.1–9.8 |
| F | 777 | 68% | 3.9 | (3.8–4.0) | 14.2 | (13.6–14.5) | 1146 | 3.8 | (3.7–4.0) | 17.4 | (16.5-19.4) | 4.1–9.8 | |
| Platelets x 109/L | M | 131 | 29% | 144 | (117–164) | 374 | (351–412) | 448 | 98 | (80–135) | 441 | (405–544) | 164–370 |
| F | 979 | 86% | 156 | (147–165) | 486 | (461–536) | 1139 | 140 | (121–151) | 495 | (464–536) | 164–370 | |
| Sodium mmol/L | F | 474 | 52% | 134 | (133–135) | 145 | (145–146) | 912 | 133 | (131–133) | 145 | (145–146) | 137–145 |
| TSH mIU/L | M | 320 | 98% | 0.48 | (0.42–0.63) | 4.93 | (4.54–5.48) | 326 | 0.46 | (0.34–0.61) | 4.93 | (4.54–5.72) | 0.24–3.78 |
| F | 852 | 91% | 0.14 | (0.07–0.25) | 5.52 | (4.83–6.36) | 937 | 0.07 | (0.02–0.11) | 6.1 | (5.21–6.63) | 0.24–3.78 | |
|
eGFR ml/min/1.73m2 |
M | 131 | 35% | 67 | (54–69) | 117 | (113–123) | 374 | 40 | (35–45) | 117 | (113–119) | > 60 |
| F | 232 | 25% | 56 | (49–64) | 116 | (113–122) | 930 | 35 | (28–42) | 123 | (120–124) | > 60 | |
Table presents estimated reference limits for patients with rheumatoid arthritis. See footnote for Table 1 for explanations.