Table 3.
(A) Two by Two table for diagnostic performance of mAb 18B7 ICT strip against CSF samples compared with the rapid test of CrAg® IMMY; (B) Summary of diagnostic performance of mAb 18B7 ICT strip with CSF samples.
| (A) | |||
| mAb 18B7 ICT Strip | Rapid Test of CrAg® IMMY | Total | |
|
Cryptococcosis
(Positive) |
Non-Cryptococcosis
(Negative) |
||
| Positive | 26 (TP) * |
0 (FP) * |
26 |
| Negative | (FN) * | 25 (TN) * |
27 |
| Total | 28 | 25 | 53 |
| (B) | |||
| Diagnostic Performance Criteria for CSF | Percentages (95% C.I.) | ||
| Sensitivity | 92.86% (76.27–99.10) | ||
| Specificity | 100% (84.24–100) | ||
| Positive predictive value | 100% (84.76–100) | ||
| Negative predictive value | 92.59% (75.53–99.04) | ||
| Accuracy | 96.23% (86.51–99.69) | ||
| Cohen’s kappa coefficient (κ) | 0.925 (0.822–1.000) | ||
* TP, True-Positive; TN, True-Negative; FP, False-Positive; FN, False-Negative.