Table 4.
(A) Two by Two table for diagnostic performance of mAb 18B7 ICT strip against serum samples compared with the rapid test of CrAg® IMMY; (B) Summary of diagnostic performance of mAb 18B7 ICT strip with serum samples.
| (A) | |||
| mAb 18B7 ICT Strip | Rapid Test of CrAg® IMMY | Total | |
|
Cryptococcosis
(Positive) |
Non-Cryptococcosis
(Negative) |
||
| Positive | 50 (TP) * |
1 (FP) * |
51 |
| Negative | 2 (FN) * |
44 (TN) * |
46 |
| Total | 52 | 45 | 97 |
| (B) | |||
| Diagnostic Performance Criteria for Serum | Percentages (95% C.I.) | ||
| Sensitivity | 96.15% (86.28–99.68) | ||
| Specificity | 97.78% (87.37–99.94) | ||
| Positive predictive value | 98.04% (88.73–99.95) | ||
| Negative predictive value | 96.65% (85.16–99.47) | ||
| Accuracy | 96.91% (91.23–99.36) | ||
| Cohen’s kappa coefficient (κ) | 0.938 (0.869–1.000) | ||
* TP, True-Positive; TN, True-Negative; FP, False-Positive; FN, False-Negative.