Figure 1.

Proliferation/viability of primary human gingival fibroblasts grown on different surfaces. hGFs were cultured on smooth machined zirconia (ZrM), sand-blasted acid-etched moderately rough zirconia (ZLA), smooth machined titanium (TiM), sand-blasted acid-etched moderately rough titanium (SLA) surfaces, and tissue culture plastic (TCP). Cell proliferation/viability was measured by CCK-8 method after 2 and 7 days of culture. Y-axis shows the optical density values measured at 450 nm. Data are presented as mean ± SEM of 8 independent experiments with cells isolated from 8 different healthy donors. *—significant difference between the groups (p ≤ 0.05).